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A study of 341 FDA trials conducted between 2017 and 2023 found that only 6% reflected US racial demographics, with declining participation among Black and Hispanic patients.

Researchers developed an AI antibody model that accurately predicts heavy and light chain pairing, challenging long-held assumptions and advancing therapeutic design.

Researchers at Institute of Science Tokyo developed adult human kidney tubuloids that model chronic kidney disease progression.

A large UBC-led study shows COVID-19 vaccination significantly reduces hospitalization, ICU admission, and preterm birth. Protection remained strong across Delta and Omicron waves, with added benefits when vaccination occurred during pregnancy.

Delta-9-tetrahydrocannabinol) and CBD (cannabidiol) from cannabis show promising anti-cancer effects on ovarian cancer cells. Both reduce cell growth, and together they may kill existing cells, pointing to potential new treatments.

A study of elite footballers shows injuries sustained during menstruation are not more frequent, but do result in significantly longer recovery times. The findings suggest hormonal and physiological changes during bleeding may worsen injury severity.

UMBC scientists uncovered how enteroviruses initiate replication by assembling a conserved RNA–protein complex inside host cells. The team showed how viral and host proteins bind an RNA cloverleaf to control replication.

Mount Sinai researchers developed a first-in-class cell-selective modRNA translation system that turns therapeutic genes on only in target cells.

Researchers identified a previously hidden RNA molecule that regulates cholesterol production by activating SREBP2, a key metabolic regulator. Blocking this RNA lowered cholesterol and reduced atherosclerosis in mice.

Scripps Research chemists developed a one-step, stereoselective method to add fluorine to drug-like molecules using inexpensive fluoride salts, overcoming a decades-old challenge and enabling faster drug development and PET imaging.