News

Discover the phase 3 trial results for a monthly injection designed to help asthma sufferers reduce or cease their use of daily steroid tablets.

mRNA therapy encoding antimicrobial peptibodies reduces drug-resistant pneumonia severity in preclinical models and boosts immune defense.

Rocatinlimab treatment for eczema has shown significant improvement in patients with moderate-to-severe atopic dermatitis.

A trial in adults with type 1 diabetes found that metformin does not improve insulin resistance in liver, muscle or fat tissue. However, it lowered daily insulin needs by ~12%, offering a practical benefit independent of insulin sensitivity.

Researchers show statins force open RyR1 calcium channels in muscle cells, revealing the cause of muscle damage and paths to safer drugs.

Researchers measured, for the first time, how mitochondria in human tissues use ketone bodies for energy. Heart, muscle and liver cells from people with type 2 diabetes or MASLD showed reduced ketone-driven energy production.

Study shows many kinase inhibitors also induce target protein degradation, revealing a widespread and exploitable pharmacological effect.

A new study outlines that most of the benefits of hormone therapy for prostate cancer occur in the first 9 to 12 months, and extending therapy increases the risk of health problems.

Methamphetamine reduces palmitoylation on dopamine transporters, slowing dopamine reuptake and altering brain signaling. The findings reveal a new mechanism behind addiction and may guide future treatments.

Three-year-old Ollie Chu, born with the rare and life-limiting Hunter syndrome, is showing improvement after receiving an experimental stem cell gene therapy developed at the University of Manchester.