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Latest App Notes & Case Studies

Scientist working with a single-use bioreactor system for advanced process development.
App Note / Case Study

Transform Process Development Efficiency With Single-Use Bioreactors

This application note explores how an advanced 5 L single-use bioreactor enhances productivity, reduces costs and enables seamless scalability from bench to production.
Speech bubble sign with the words "FIND CANCER EARLY" on a gray background; "EARLY" is highlighted in red.
App Note / Case Study

Advancing Early Cancer Detection Research

This application note highlights how methylation sequencing and custom capture panels improve sensitivity and specificity, opening new possibilities for liquid biopsy research.
Two pages of the Modeling Tau Pathology With Human Brain Organoids app note on a grey background.
App Note / Case Study

Modeling Tau Pathology With Human Brain Organoids

This application note highlights a mature 3D organoid model that combines cerebral organoids with tau preformed fibrils to support mechanistic research and therapeutic screening in a human-relevant setting.
Microscopic view of multiplying cancer cells in a dark fluid environment.
App Note / Case Study

Optimize CAR T-Cell Manufacturing Efficiency

This application note explores how advanced SFM formulations can dramatically improve CRISPR-modified CAR-T cell production while maintaining GMP compliance and scalability.
Agilent report on TGF-β activity in angiogenesis research.
App Note / Case Study

High-Throughput, Quantitative Evaluation of TGF-β Signaling in Angiogenesis

This application note highlights how combining a phosphorylation and translocation assay with a confocal imaging reader can provide a robust and sophisticated method for analyzing the magnitude of SMAD activation. This in turn provides quantitative e
Case study document showing lab technicians and equipment used for automating NGS-based HLA typing for stem cell transplantations
App Note / Case Study

Optimizing Donor Matching With Automated HLA Typing

This case study explores how a leading institution in histocompatibility implemented an automated NGS-based workflow for high-resolution HLA typing.
Twist Bioscience and IntegraGen application note detailing NGS liquid biopsy solution for MRD detection with graphs and methodology
App Note / Case Study

Advanced MRD Detection Using Liquid Biopsy

This application note outlines a comprehensive workflow for MRD detection, using a next-generation sequencing (NGS) approach to enable ultra-sensitive analysis with unmatched precision.

Refeyn application note on forced antibody degradation using automated mass photometry, featuring sample data graph and descriptive text
App Note / Case Study

Mass Photometry in a Forced Antibody Degradation Study

In this application note, discover how mass photometry can be used to analyze the fragmentation and aggregation of therapeutic antibodies in response to stressors like light, pH variations, and peroxide exposure.
Cover of a Refeyn technical note on antibody aggregation analysis using mass photometry as a column-free method orthogonal to SEC-UV, featuring blue antibody structures on a dark background
App Note / Case Study

Mass Photometry, a Column-Free Orthogonal to SEC-UV

In this technical note, we explore datasets captured through mass photometry and size exclusion chromatography (SEC), comparing how they characterize the aggregation levels in different biosimilar antibodies
Image Of A Blue Engineered T-cell attacks a red cancer cell
App Note / Case Study

High-Throughput Verification of CAR T-Cell Function

This app note highlights a novel picodroplet-based platform that provides rapid, high-throughput assessment of cell product fitness, offering a valuable tool for both QC release and early-stage research.
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