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New Role for Gut Bacteria in Pregnancy Success
A preclinical study from Weill Cornell Medicine shows that beneficial gut microbes help prevent pregnancy loss by promoting immune tolerance to the fetus.
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Learning a Musical Instrument Improves Cognitive Function in Older People
Learning a musical instrument, particularly through improvisation, could boost cognitive skills such as learning and memory in older adults.
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Genome Differences May Explain Why Some Antibody Drugs Fail
Common genetic variants can prevent antibody therapies from binding their targets, reducing treatment effectiveness. The study shows how small amino acid changes can block drug binding.
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How Traumatic Brain Injury Increases Alzheimer's Risk
New research reveals why traumatic brain injury increases Alzheimer's risk, and points to a potential preventative strategy.
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Microscopy Captures Synapses in Action for the First Time
Using cryo-electron microscopy, researchers have detailed the synaptic vesicle fusion process, which is crucial for effective neurotransmitter release in the brain.
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Ultra-Processed Diets Alter Gut Microbe Evolution
UCLA researchers found that gut bacteria are rapidly evolving in response to modern diets. Genes enabling digestion of industrial starches have spread quickly through microbial genomes via horizontal gene transfer.
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AI-Designed Molecule Boosts Chemotherapy Response in Pancreatic Cancer
Researchers at the Italian Institute of Technology developed an AI-designed aptamer that disrupts DNA repair in pancreatic cancer cells. The molecule, Apt1, increases tumor sensitivity to chemotherapy drugs such as olaparib, even at lower doses.
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"Zombie" Cells Spark Inflammation in Severe Fatty Liver Disease
Mayo Clinic scientists discovered that senescent “zombie” cells trigger inflammation by leaking mitochondrial RNA, activating immune sensors that accelerate liver scarring and the progression of MASH.
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Blood Analysis Shows Whether Glioblastoma Treatment Is Working
Researchers found that a blood analysis performed after opening the blood-brain barrier can track glioblastoma response to chemotherapy, enabling faster and more precise treatment decisions.
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Limited Diversity in FDA Trials Could Impact Drug Safety and Efficacy
A study of 341 FDA trials conducted between 2017 and 2023 found that only 6% reflected US racial demographics, with declining participation among Black and Hispanic patients.
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