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Researchers have extracted metabolism-related molecules from fossilized animal bones up to 3 million years old. The metabolites revealed information about diet, disease, sex and environmental conditions.

Researchers at the Italian Institute of Technology developed an AI-designed aptamer that disrupts DNA repair in pancreatic cancer cells. The molecule, Apt1, increases tumor sensitivity to chemotherapy drugs such as olaparib, even at lower doses.

Mayo Clinic scientists discovered that senescent “zombie” cells trigger inflammation by leaking mitochondrial RNA, activating immune sensors that accelerate liver scarring and the progression of MASH.

UMass Amherst chemists have developed a three-color fluorescent method to visualize different mRNA molecules inside living mammalian cells. The approach reduces background noise and enables real-time tracking of RNA behavior.

Researchers have uncovered differences in how multiple myeloma develops and progresses in men and in women, which could lead to earlier detection and sex-specific treatments.

SickKids researchers discovered that a long non-coding RNA, CISTR-ACT, directly regulates cell size. Using gene-editing tools, they showed that increasing CISTR-ACT shrinks cells, while removing it makes cells larger.

Penn State researchers discovered that two proteins within the CCR4-NOT complex have opposing effects on mRNA stability. Using a precision protein-degradation tool in human cancer cells, the team showed that one protein slows mRNA decay.

Research shows how cells respond to brain injury by releasing corticotropin-releasing hormone, which helps to repair damage.

A study finds that a single gut bacterium can lower blood sugar, reduce fat accumulation and limit weight gain in mice. The microbe produces fatty molecules that counter harmful metabolic effects of high-fat diets.

Researchers found that higher blood levels of theobromine, a compound found in cocoa, were linked to slower biological aging. Using DNA-based aging markers in two European cohorts, the study showed the association was independent of caffeine.