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Latest Articles

Modern LC-MS/MS mass spectrometer in a proteomics laboratory with monitors displaying mass spectral data and chromatograms.
Article

Mass Spectrometry for Proteomics: Techniques, Tools and Tips

Master mass spectrometry for proteomics with this guide on techniques like LC-MS/MS, MALDI, and DIA vs DDA to enhance laboratory workflows and data.
Digital human figure dissolving into colored data blocks, symbolizing spatial biology and cellular mapping.
Article

Spatial Biology: A New Frontier in Understanding Biological Systems

This article explores how researchers are using spatially resolved methods to explore diverse biological processes from development and tumorigenesis to fibrosis, neurodegeneration, infection and inflammation.
3D illustration of an RNA strand on a gradient background, representing RNA therapeutics research.
Article

Addressing Development Challenges for RNA Therapeutics

This article explores how challenges such as sequence optimization, immune activation and off-target effects are being addressed to enhance the safety, durability and efficacy of RNA therapeutics.
Visual representation of molecular profiling with DNA and a human figure.
Article

Proteomics vs Genomics: Key Differences in Molecular Profiling

Comparing proteomics to genomics reveals essential insights into their contributions to systems biology and experimental design. Learn how the different omics layers advances molecular profiling.
Medical professional gently handling a newborn baby, representing infant care and SIDS awareness.
Article

Newborn Blood Drops Reveal Early Clues to SIDS Risk

A high-throughput proteomics study of newborn dried blood spots uncovered a three-protein biomarker panel that distinguished preterm infants who later died of SIDS from matched controls, highlighting biological differences in preterm SIDS cases.
Abstract digital figure made of blocks and molecules representing proteomics and human biology.
Article

Inside the UK Biobank’s Push Toward Population-Scale Proteomics

UK Biobank’s expansion of Olink proteomics from 50,000 to 500,000 participants marks a major step toward true population-scale multi-omics. Deputy Chief Scientist Dr. Adam Lewandowski discusses the challenges of releasing this high-dimensional data.
High-resolution mass spectrometer visualizing complex proteomics data transformation.
Article

Navigating the Proteome: A Comprehensive Proteomics Glossary for Researchers

A definitive guide to proteomics definitions, mass spectrometry terminology, and key concepts in quantitative proteomics for life science researchers and lab scientists.
Abstract scientific visualization illustrating middle-down proteomics bridging the gap.
Article

Middle-Down Proteomics: Bridging Bottom-Up and Top-Down

Middle-down proteomics addresses the limitations of conventional bottom-up approaches by providing deeper insight into proteoform analysis.
Dynamic, abstract depiction of top-down proteomics.
Article

Top-Down Proteomics Explained: Advantages and Challenges in Intact Protein Analysis

A detailed examination of top-down proteomics and its critical role in comprehensive proteoform identification using advanced mass spectrometry techniques.
Abstract visualization of bottom-up proteomics, showing proteins fragmenting into peptides within a mass spectrometer.
Article

Deconvoluting the Proteome: Principles and Advances in Bottom-Up Proteomics

A comprehensive overview of bottom-up proteomics, detailing the critical stages from protein digestion and peptide analysis to mass spectrometry detection.
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