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Mass Spectrometry for Proteomics: Techniques, Tools and Tips
Master mass spectrometry for proteomics with this guide on techniques like LC-MS/MS, MALDI, and DIA vs DDA to enhance laboratory workflows and data.
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Spatial Biology: A New Frontier in Understanding Biological Systems
This article explores how researchers are using spatially resolved methods to explore diverse biological processes from development and tumorigenesis to fibrosis, neurodegeneration, infection and inflammation.
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Addressing Development Challenges for RNA Therapeutics
This article explores how challenges such as sequence optimization, immune activation and off-target effects are being addressed to enhance the safety, durability and efficacy of RNA therapeutics.
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Proteomics vs Genomics: Key Differences in Molecular Profiling
Comparing proteomics to genomics reveals essential insights into their contributions to systems biology and experimental design. Learn how the different omics layers advances molecular profiling.
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Newborn Blood Drops Reveal Early Clues to SIDS Risk
A high-throughput proteomics study of newborn dried blood spots uncovered a three-protein biomarker panel that distinguished preterm infants who later died of SIDS from matched controls, highlighting biological differences in preterm SIDS cases.
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Inside the UK Biobank’s Push Toward Population-Scale Proteomics
UK Biobank’s expansion of Olink proteomics from 50,000 to 500,000 participants marks a major step toward true population-scale multi-omics. Deputy Chief Scientist Dr. Adam Lewandowski discusses the challenges of releasing this high-dimensional data.
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Navigating the Proteome: A Comprehensive Proteomics Glossary for Researchers
A definitive guide to proteomics definitions, mass spectrometry terminology, and key concepts in quantitative proteomics for life science researchers and lab scientists.
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Middle-Down Proteomics: Bridging Bottom-Up and Top-Down
Middle-down proteomics addresses the limitations of conventional bottom-up approaches by providing deeper insight into proteoform analysis.
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Top-Down Proteomics Explained: Advantages and Challenges in Intact Protein Analysis
A detailed examination of top-down proteomics and its critical role in comprehensive proteoform identification using advanced mass spectrometry techniques.
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Deconvoluting the Proteome: Principles and Advances in Bottom-Up Proteomics
A comprehensive overview of bottom-up proteomics, detailing the critical stages from protein digestion and peptide analysis to mass spectrometry detection.
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