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Latest App Notes & Case Studies

Sensitive bioanalysis of galactosyl sphingosine (GalSPH) and  glucosyl sphingosine (GluSPH) in cerebral spinal fluid
App Note / Case Study

Breakthrough Sensitivity for Glycosphingolipid Biomarkers

This app note highlights an optimized HILIC-MS/MS approach that significantly enhances signal strength for GalSPH and GluSPH analysis in CSF.
Improving assay efficiency for blood-brain barrier (BBB) integrity biomarker quantitation in neurovascular disorder  research using microflow LC-MS/MS
App Note / Case Study

Sensitive Biomarker Quantitation in Brain Tissue

This app note highlights an optimized microflow LC-MS/MS approach that significantly enhances signal strength for biomarker quantitation in laser microdissected brain tissue.
Abstract AI medical technology concept illustrating protein biomarker analysis for early drug discovery.
App Note / Case Study

Advancing Sensitivity in Protein Quantification

This app note highlights an antibody-free, microflow LC-MS approach that enhances signal strength and precision for surfactant protein quantification.
Papers from real-Time Metabolic Analysis in 3D Brain Models application note on a grey background.
App Note / Case Study

Real-Time Metabolic Analysis in 3D Brain Models

This app note highlights an optimized system for assessing mitochondrial respiration and glycolysis in brain tissue slices. It introduces a workflow that enables real-time, high-sensitivity metabolic profiling with consistent, reproducible results.
3D illustration of blue and white protein structures representing enhanced protein expression through Poly(A) innovation.
App Note / Case Study

Boost Protein Expression With Poly(A) Innovation

This technical note explores a novel poly(A) tail modification that enhances total protein expression and extends expression duration across multiple constructs and cap structures, without increasing immune response.
Scientist working with a single-use bioreactor system for advanced process development.
App Note / Case Study

Transform Process Development Efficiency With Single-Use Bioreactors

This application note explores how an advanced 5 L single-use bioreactor enhances productivity, reduces costs and enables seamless scalability from bench to production.
Scientist holding a blood sample tube for pTau 217 assay testing in Alzheimer’s research lab.
App Note / Case Study

An Innovative pTau 217 Assay Unlocks New Possibilities in Alzheimer’s Disease Research

This case study shows how a next-generation pTau 217 assay achieves higher accuracy than existing platforms using only 1 µL of diluted plasma, while maintaining robust performance across freeze-thawed samples and diverse cohorts.
Scientist examining a sample under a microscope in a forensic toxicology laboratory.
App Note / Case Study

Expand NPS Detection With High-Resolution Screening

This app note highlights a LC-MS/MS workflow that enhances NPS detection, enabling confident screening of over 900 compounds in complex biological matrices with a single injection.
An application note on reducing dsRNA during mRNA synthesis using novel RNA polymerase.
App Note / Case Study

Preventing Double-Stranded RNA Formation in mRNA Manufacturing

This application note highlights how a novel RNA polymerase provides a seamless solution that reduces dsRNA formation, minimizing the need for additional purification steps while maintaining superior mRNA quality and yield.
Colorful 3D rendering of a protein structure showing intricate folding and molecular detail.
App Note / Case Study

Leveraging Automation To Enhance Protein Analysis

This application note demonstrates how an automated parallel CE-SDS system can provide reliable measurements from 1 µL of protein crude lysate in just 30 minutes.
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