News

A Mount Sinai team showed that the same leukemia mutation behaves differently depending on when it arises during development. Using CRISPR in human blood stem cells, they found prenatal-origin leukemias are more aggressive and treatment-resistant.

Researchers used CRISPR screening in tumor organoids and mice to identify two genes, Ctnna1 and Bcl2l13, that suppress colorectal cancer metastasis. One limits cell invasion, while the other triggers cell death after detachment.

Researchers have characterised the structure and function of a key protein that helps breast cancer cells survive.

Cornell researchers used an engineered rabies virus to trace how psilocybin reshapes neural circuits, weakening cortical feedback loops linked to rumination and strengthening the link between perception and action.

A new study has revealed that T cells in certain tissues of the body differ in significant ways from those in the blood, which could have implications for how the effectiveness of vaccines and immunotherapies are evaluated in the future.

Biotech and pharma greenhouse gas emissions are falling – but is current progress fast enough? Discover My Green Lab’s Impact Report.

A new RNA type, smOOPs, has been found to drive biomolecular condensate formation in early development, offering new insight into cell function and disease mechanisms.

KAIST researchers have developed a method that attaches DNA fragments to mRNA to slow the onset of protein production, reducing dangerous spikes linked to side effects and enabling personalized, safer mRNA therapies.

When exposed to green light, the protein AR3 increases alkalinity in cells, disrupting cellular functions and causing apoptosis.

Researchers have uncovered a mechanism that protects nerve cells from premature cell death, providing the first molecular evidence that ferroptosis can drive neurodegeneration.