News

MIT researchers have synthesized verticillin A, a complex fungal compound discovered more than 50 years ago and long recognized for its anticancer potential. The compound’s fragile structure and precise stereochemistry make it difficult to produce.

A Phase 3 trial found that combining eflornithine with lomustine significantly improved survival for patients with recurrent grade 3 IDH-mutant astrocytoma, extending life by nearly a year compared with standard therapy.

When exposed to green light, the protein AR3 increases alkalinity in cells, disrupting cellular functions and causing apoptosis.

Researchers have identified a protein responsible for activating RAS signaling pathways in aggressive tumors, offering a complementary therapeutic avenue.

New research finds that cancer cells with a more easily deformed nucleus are more sensitive to DNA-damaging drugs.

New research shows how breast cancer makes significant molecular changes in lymphatic vessels as it metastasizes to the lymph nodes.

Researchers have developed a new antibody that could help to destroy hard-to-treat tumours more effectively, with fewer side effects than some current therapies.

New research has illustrated how cancer cells maintain their telomeres to keep dividing.

A new study demonstrates that replicative senescence depends upon ATM kinase, and that high oxygen generates a hyperactive form of ATM that forces cells to arrest earlier.

A new epidemiological study from Lund University in Sweden suggests that tattoos could be a risk factor for melanoma.