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Latest App Notes & Case Studies

Bioluminescent imaging of mice comparing CleanCap AG, AG 3' OMe, and M6 mRNA expression levels
App Note / Case Study

Streamlined mRNA Capping Strategies for Enhanced Therapeutic Potential

This application note explores how these cutting-edge capping strategies enhance mRNA potency, stability and expression, providing valuable insights for researchers and manufacturers.
Brochure on E. coli fermentation scale-up from 200L stainless steel to 1000L single-use fermenter
App Note / Case Study

Successful Scale-Up for High-Density Microbial Processes

This application note highlights the successful 5-fold scale-up of a high-cell density E. coli process from an established 200 L stainless steel fermenter to a 1000 L single-use system.
Close up of a womens hand in a glove with a test tube.
App Note / Case Study

Optimizing Metabolite Identification With Electron-Activated Dissociation

This app note highlights the advantages of electron-activated dissociation (EAD) in identifying oxidative metabolites of the molecular glue, mezigdomide.
Scientist wearing blue gloves using a multichannel pipette to transfer liquid into a 96-well plate in a laboratory, with reagent bottles and test tubes in the background
App Note / Case Study

Enhance Protein Quality Analysis With CE-SDS

This app note highlights the benefits of an automated capillary electrophoresis (CE) system for protein quality control. By enabling high-resolution analysis with minimal sample input, this approach streamlines workflows while improving accuracy
Scientist wearing safety goggles and a yellow glove handling labeled vials in a laboratory
App Note / Case Study

Enhance Patient Safety With PCR-Based Rapid Sterility Testing

This application note presents a comprehensive study comparing an ATMP release kit with an alternative PCR-based solution, evaluating both sensitivity and workflow convenience for ATMP quality control laboratories.
Scientist observing a floating 3D-rendered antibody-drug conjugate (ADC) structure with glowing markers, symbolizing targeted therapy.
App Note / Case Study

3D Tumor Models for More Predictive ADC Drug Development

This application note demonstrates a novel workflow for comprehensive ADC evaluation in 3D tumor spheroid models, offering deeper insights into drug function and cellular response.
Attune Xenith flow cytometry optical deck enabling precise, high-speed cell analysis with advanced detection technology.
App Note / Case Study

Optimized Flow Cytometry for Natural Killer Cell Analysis

This application note explores an innovative spectral flow cytometry method optimized for NK cell characterization.
3D-rendered illustration of biological cells with a translucent outer membrane and a textured pink core, floating in a white background.
App Note / Case Study

Boost Biopharmaceutical Productivity With Peptone Solutions

This application note demonstrates how carefully selected peptones can revolutionize biomanufacturing processes.
Cover for application note featuring guidelines on contamination management and laboratory balance maintenance
App Note / Case Study

How To Manage Contamination of Your Analytical Balance

This application note explores how a new generation of modern analytical balances benefit from hardware and software features that make cleaning processes easier and safer.
3D rendering of antibody-drug conjugates (ADCs) in a blue molecular environment, showcasing complex antibody structures.
App Note / Case Study

Streamlining the Analysis of Free Drug Content in ADCs

This application note presents a method that integrates protein elimination and free drug identification into one analysis using a two-dimensional liquid chromatography/quadrupole time-of-flight mass spectrometry (2D-LC/Q-TOF) approach.
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