Latest How To Guides

Since the discovery of elevated levels of nitrosamines in certain pharmaceuticals, reported in July 2018, finding the right solutions have become a major focus for many pharmaceutical manufacturers, particularly as they are considered probable human carcinogens.

Messenger RNA (mRNA) therapy enables the body to make the proteins needed to prevent, treat or cure diseases but, unlike traditional biologics, mRNAs are large and delicate molecules that need to be protected by lipid nanoparticles (LNPs) on the journey to reach target cells.

This guide highlights the four major stages of targeted protein degradation, the challenges at each step, and the questions you should ask yourself to ensure your final product will result in a complete protein degradation.

Mitochondrial toxicity assessments are crucial to ensuring the safety and efficacy of candidate compounds during drug development.

Download this guide to learn more about laboratory automation and the novel informatics solutions available to ensure sound and long-lasting investments.

Download this guide to learn more about automated software and the latest solutions available.

Download this guide to learn more about automated liquid handling solutions.

Download this guide to discover how data integrity is fundamental to quality assurance, process development and production, and analytical development and quality control.

These living cultures often respond to our mistakes not only by the erratic behavior common to other laboratory tools, but by dying – the total, irreplaceable destruction of the tool itself.

For UV-Visible spectrophotometers in regulated laboratories, performance verification (PV) at installation and at set intervals thereafter is needed, however, the selection of standards for use in PV testing can be challenging.