Latest App Notes & Case Studies

This app note focuses on the analysis of oligonucleotides using HILIC conditions to compare traditional stainless-steel High Performance Liquid Chromatography (HPLC) Systems and columns with systems and columns employing MaxPeak HPS Technology

On the Alliance iS HPLC System, the optional 690 µL Ti diffusion bonded mixer improved baselines, enabled more reproducible peak integration, and increased sensitivity compared to that of the binary and the quaternary systems with standard mixers

The Alliance iS HPLC System with Photodiode Array (PDA) Detector separates and identifies compounds, determines spectral purity, and visualizes UV absorptive regions for chemical UV filters used in sunscreen lotion formulations.

In this study, the United States Pharmacopeia (USP) propofol assay normal-phase method was successfully modernized on the Alliance™ iS HPLC PDA System using a modern column.

In this study, the USP method for organic impurities in ibuprofen tablets was used to demonstrate how optimizing detector settings produced an improvement in sensitivity.

This app note explores how switching the draw-out lens impacts sensitivity and resolution with hydrogen versus helium, across various flow rates and detection modes.

This application note highlights a complete extraction-to-analysis method that offers the exceptional sensitivity and robust quantitation needed to analyze nine nitazene analogs and brorphine in DBS samples.

Proactive detection and risk mitigation are essential to ensure product safety and compliance with future regulations. This app note showcases a comprehensive screening solution that can ensure targeted and accurate PFAS screening.

This application note assesses an LC-MS strategy for testing manufacturing components for PFAS, even at sub-ppb levels, ensuring reliable results.

This application note demonstrates how advanced multi-quadrupole ICP-MS technology can revolutionize ultra-pure NMP analysis for effective semiconductor manufacturing quality control.