News

Roswell Park scientists show that IL-36γ–armored CAR T cells reprogram neutrophils to trigger powerful immune responses against solid tumors.

A Dartmouth study reveals how LACTB reshapes the inner membrane trigger apoptosis, opening new paths for cancer and neurodegenerative therapies.

A study profiling antigens presented on immune and tumor cells in co-culture points to new strategies for attacking a treatment-resistant and deadly brain cancer.

A new study reveals that tanning beds cause melanoma-linked DNA damage across almost the entire skin surface, explaining the nearly threefold rise in melanoma risk seen in users. Single-cell sequencing showed widespread mutations.

A new modeling study suggests that current HPV vaccination programs reduce cervical cancer but are insufficient for elimination. Expanding coverage to more girls or including boys could achieve herd immunity and end HPV-related cancers.

New research has identified key factors that drive lung tumor evolution and influence outcomes, describing a previously unknown origin of some aggressive lung cancers.

Real-time imaging has tracked what happens to cancer cells arriving in the brain, identifying a new strategy to prevent brain tumors.

A new type of CAR T-cell therapy elicits a more controlled immune response to cancer in mice, effectively killing cancer cells with fewer side effects.

Reducing calorie intake helps cancer-fighting immune cells do their jobs more effectively, laying the groundwork for developing dietary strategies to boost cancer immunotherapy.

PVEK, a CD123-targeting antibody-drug conjugate, demonstrated strong response rates in two studies. Combined with VEN/AZA, it produced high remissions in CD123-positive AML and as monotherapy, it delivered high responses in high-risk BPDCN patients.