News

Researchers identified genetic variants in two lung-related proteins that alter the risk of retinopathy of prematurity. Some variants increased risk, while others were protective, acting opposite to their effects in the lungs.

A new study reveals that tanning beds cause melanoma-linked DNA damage across almost the entire skin surface, explaining the nearly threefold rise in melanoma risk seen in users. Single-cell sequencing showed widespread mutations.

Researchers developed a dual-channel AID system that allows precise, lifelong tuning of protein levels in specific tissues of C. elegans. The method overcomes major limits of traditional on/off genetic tools.

CSHL researchers used CRISPR to rapidly domesticate goldenberries, a nutritious but unruly fruit. By editing growth genes, they created plants 35% shorter and easier to harvest, then bred tastier lines across generations.

Researchers found that polar bears in southeastern Greenland show heightened activity of "jumping genes" linked to heat stress, metabolism and aging. These DNA changes appear tied to rising temperatures and shrinking sea ice.

New research has identified key factors that drive lung tumor evolution and influence outcomes, describing a previously unknown origin of some aggressive lung cancers.

A study scanned genomes from over 450,000 people to find individuals who carry rare archaic versions of DNA changes once thought universal in humans. The research shows that some high-profile evolutionary genes may have smaller real-world effects.

Researchers from Gladstone Institutes and Stanford developed a genomic mapping method that links complex traits to the gene networks controlling them. The team identified how individual genes influence multiple biological pathways.

A massive genomic study of over 1 million cases found that shared risk across 14 psychiatric disorders is reduced to 5 underlying genetic factors. Researchers linked each factor to specific brain cell types and identified genetic hotspots.

Researchers developed hQTL-ODS, a fast statistical method that maps how interacting genes drive heterosis, or hybrid vigor. Applied to more than 5,000 wheat hybrids, the tool identified key genetic networks in days instead of years.